The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-κB p65

Many bacterial pathogens utilize a type III secretion system to deliver multiple effector proteins into host cells. Here we found that the type III effectors, NleE from enteropathogenic E. coli (EPEC) and OspZ from Shigella, blocked translocation of the p65 subunit of the transcription factor, NF-κB...

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Bibliografische gegevens
Hoofdauteurs: Newton, Hayley J., Pearson, Jaclyn S., Badea, Luminita, Kelly, Michelle, Lucas, Mark, Holloway, Gavan, Wagstaff, Kylie M., Dunstone, Michelle A., Sloan, Joan, Whisstock, James C., Kaper, James B., Robins-Browne, Roy M., Jans, David A., Frankel, Gad, Phillips, Alan D., Coulson, Barbara S., Hartland, Elizabeth L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869321/
https://ncbi.nlm.nih.gov/pubmed/20485572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000898
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