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Broad activation of latent HIV-1 in vivo

The ‘shock and kill' approach to cure human immunodeficiency virus (HIV) includes transcriptional induction of latent HIV-1 proviruses using latency-reversing agents (LRAs) with targeted immunotherapy to purge infected cells. The administration of LRAs (panobinostat or vorinostat) to HIV-1-infe...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Barton, Kirston, Hiener, Bonnie, Winckelmann, Anni, Rasmussen, Thomas Aagaard, Shao, Wei, Byth, Karen, Lanfear, Robert, Solomon, Ajantha, McMahon, James, Harrington, Sean, Buzon, Maria, Lichterfeld, Mathias, Denton, Paul W., Olesen, Rikke, Østergaard, Lars, Tolstrup, Martin, Lewin, Sharon R., Søgaard, Ole Schmeltz, Palmer, Sarah
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025526/
https://ncbi.nlm.nih.gov/pubmed/27605062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12731
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