Broad activation of latent HIV-1 in vivo

The ‘shock and kill' approach to cure human immunodeficiency virus (HIV) includes transcriptional induction of latent HIV-1 proviruses using latency-reversing agents (LRAs) with targeted immunotherapy to purge infected cells. The administration of LRAs (panobinostat or vorinostat) to HIV-1-infe...

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Foilsithe in:Nat Commun
Main Authors: Barton, Kirston, Hiener, Bonnie, Winckelmann, Anni, Rasmussen, Thomas Aagaard, Shao, Wei, Byth, Karen, Lanfear, Robert, Solomon, Ajantha, McMahon, James, Harrington, Sean, Buzon, Maria, Lichterfeld, Mathias, Denton, Paul W., Olesen, Rikke, Østergaard, Lars, Tolstrup, Martin, Lewin, Sharon R., Søgaard, Ole Schmeltz, Palmer, Sarah
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025526/
https://ncbi.nlm.nih.gov/pubmed/27605062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12731
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