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Werner Syndrome: Clinical Features, Pathogenesis and Potential Therapeutic Interventions
Werner syndrome (WS) is a prototypical segmental progeroid syndrome characterized by multiple features consistent with accelerated aging. It is caused by null mutations of the WRN gene, which encodes a member of the RECQ family of DNA helicases. A unique feature of the WRN helicase is the presence o...
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| Veröffentlicht in: | Ageing Res Rev |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025328/ https://ncbi.nlm.nih.gov/pubmed/26993153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2016.03.002 |
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