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Numb regulates the balance between Notch recycling and late-endosome targeting in Drosophila neural progenitor cells

The Notch signaling pathway plays essential roles in both animal development and human disease. Regulation of Notch receptor levels in membrane compartments has been shown to affect signaling in a variety of contexts. Here we used steady-state and pulse-labeling techniques to follow Notch receptors...

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Bibliografiska uppgifter
I publikationen:Mol Biol Cell
Huvudupphovsmän: Johnson, Seth A., Zitserman, Diana, Roegiers, Fabrice
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025272/
https://ncbi.nlm.nih.gov/pubmed/27466320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-11-0751
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