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Sanpodo controls sensory organ precursor fate by directing Notch trafficking and binding γ-secretase
In Drosophila peripheral neurogenesis, Notch controls cell fates in sensory organ precursor (SOP) cells. SOPs undergo asymmetric cell division by segregating Numb, which inhibits Notch signaling, into the pIIb daughter cell after cytokinesis. In contrast, in the pIIa daughter cell, Notch is activate...
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| Главные авторы: | , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3639393/ https://ncbi.nlm.nih.gov/pubmed/23609534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201209023 |
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