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Sanpodo controls sensory organ precursor fate by directing Notch trafficking and binding γ-secretase

In Drosophila peripheral neurogenesis, Notch controls cell fates in sensory organ precursor (SOP) cells. SOPs undergo asymmetric cell division by segregating Numb, which inhibits Notch signaling, into the pIIb daughter cell after cytokinesis. In contrast, in the pIIa daughter cell, Notch is activate...

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Main Authors: Upadhyay, Alok, Kandachar, Vasundhara, Zitserman, Diana, Tong, Xin, Roegiers, Fabrice
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639393/
https://ncbi.nlm.nih.gov/pubmed/23609534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201209023
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