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Interplay between Leucine-Rich Repeat Kinase 2 (LRRK2) and p62/SQSTM-1 in Selective Autophagy

The deposit of polyubiquitinated aggregates has been implicated in the pathophysiology of Parkinson’s disease (PD), and growing evidence indicates that selective autophagy plays a critical role in the clearance of ubiquitin-positive protein aggregates by autophagosomes. The selective autophagic rece...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Park, Sangwook, Han, Seulki, Choi, Insup, Kim, Beomsue, Park, Seung Pyo, Joe, Eun-Hye, Suh, Young Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025236/
https://ncbi.nlm.nih.gov/pubmed/27631370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163029
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