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Exposure-response analysis to assess the concentration–QTc relationship of CC-122
CC-122 hydrochloride is a novel pleiotropic pathway modifier compound that binds cereblon, a substrate receptor of the Cullin 4 RING E3 ubiquitin ligase complex. CC-122 has multiple activities including modulation of immune cells, antiproliferative activity of multiple myeloma and lymphoma cells, an...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Clin Pharmacol |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Dove Medical Press
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5024774/ https://ncbi.nlm.nih.gov/pubmed/27672344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S111867 |
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