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No Evidence of QTc Interval Prolongation With Baxdrostat Treatment: Concentration–QTc Modeling Assessment

ABSTRACT Baxdrostat is a novel, highly potent, selective, competitive inhibitor of human aldosterone synthase currently under development for the treatment of uncontrolled and resistant hypertension and chronic kidney disease. We assessed the risk of QTc‐interval prolongation with baxdrostat using c...

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Autori principali: Mikael Sunnåker, Christian Källgren, Joanna Parkinson, Corina Dota, Christer Gottfridsson, David Janzén, Anita Andersson, Glenn Carlson
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2025-10-01
Serie:Pharmacology Research & Perspectives
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Accesso online:https://doi.org/10.1002/prp2.70181
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