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Neuronal Rap1 regulates energy balance, glucose homeostasis, and leptin actions

The central nervous system (CNS) contributes to obesity and metabolic disease; however, the underlying neurobiological pathways remain to be fully established. Here we show that the small GTPase Rap1 is expressed in multiple hypothalamic nuclei that control whole-body metabolism and is activated in...

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Detalles Bibliográficos
Publicado en:Cell Rep
Main Authors: Kaneko, Kentaro, Xu, Pingwen, Cordonier, Elizabeth L., Chen, Siyu S., Ng, Amy, Xu, Yong, Morozov, Alexei, Fukuda, Makoto
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024738/
https://ncbi.nlm.nih.gov/pubmed/27626668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.039
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