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Lineage-restricted OLIG2-RTK signaling governs the molecular subtype of glioma stem-like cells
The bHLH transcription factor OLIG2 is a master regulator of oligodendroglial fate decisions and tumorigenic competence of glioma stem-like cells (GSCs). However, the molecular mechanisms underlying dysregulation of OLIG2 function during gliomagenesis remains poorly understood. Here, we show that OL...
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| Pubblicato in: | Cell Rep |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5024710/ https://ncbi.nlm.nih.gov/pubmed/27626655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.040 |
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