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Post-translational modifications of OLIG2 regulate glioma invasion through the TGFβ pathway

In glioblastoma, invasion and proliferation are presumed to be mutually exclusive events; however, the molecular mechanisms that mediate this switch at the cellular level remain elusive. Previously, we have shown that phospho-OLIG2, a Central Nervous System-specific transcription factor, is essentia...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Singh, Shiv K., Fiorelli, Roberto, Kupp, Robert, Rajan, Sindhu, Szeto, Emily, Cascio, Costanza Lo, Maire, Cecile L., Sun, Yu, Alberta, John A., Eschbacher, Jennifer, Ligon, Keith L., Berens, Michael E., Sanai, Nader, Mehta, Shwetal
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963280/
https://ncbi.nlm.nih.gov/pubmed/27396340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.045
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