Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin

Microrchidia (MORC) proteins are GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPases that function in gene regulation in multiple organisms. Animal MORCs also contain CW-type zinc finger domains, which are known to bind to modified histones. We solved the crystal structure of the mu...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Li, Sisi, Yen, Linda, Pastor, William A., Johnston, Jonathan B., Du, Jiamu, Shew, Colin J., Liu, Wanlu, Ho, Jamie, Stender, Bryan, Clark, Amander T., Burlingame, Alma L., Daxinger, Lucia, Patel, Dinshaw J., Jacobsen, Steven E.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
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PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024608/
https://ncbi.nlm.nih.gov/pubmed/27528681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609709113
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