Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin

Microrchidia (MORC) proteins are GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPases that function in gene regulation in multiple organisms. Animal MORCs also contain CW-type zinc finger domains, which are known to bind to modified histones. We solved the crystal structure of the mu...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Li, Sisi, Yen, Linda, Pastor, William A., Johnston, Jonathan B., Du, Jiamu, Shew, Colin J., Liu, Wanlu, Ho, Jamie, Stender, Bryan, Clark, Amander T., Burlingame, Alma L., Daxinger, Lucia, Patel, Dinshaw J., Jacobsen, Steven E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2016
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PNAS Plus
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024608/
https://ncbi.nlm.nih.gov/pubmed/27528681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609709113
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