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Structural conservation in the template/pseudoknot domain of vertebrate telomerase RNA from teleost fish to human

Telomerase is an RNA–protein complex that includes a unique reverse transcriptase that catalyzes the addition of single-stranded telomere DNA repeats onto the 3′ ends of linear chromosomes using an integral telomerase RNA (TR) template. Vertebrate TR contains the template/pseudoknot (t/PK) and CR4/5...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Wang, Yaqiang, Yesselman, Joseph D., Zhang, Qi, Kang, Mijeong, Feigon, Juli
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024593/
https://ncbi.nlm.nih.gov/pubmed/27531956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607411113
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