Scavenging nucleic acid debris to combat autoimmunity and infectious disease

Nucleic acid-containing debris released from dead and dying cells can be recognized as damage-associated molecular patterns (DAMPs) or pattern-associated molecular patterns (PAMPs) by the innate immune system. Inappropriate activation of the innate immune response can engender pathological inflammat...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Holl, Eda K., Shumansky, Kara L., Borst, Luke B., Burnette, Angela D., Sample, Christopher J., Ramsburg, Elizabeth A., Sullenger, Bruce A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Physical Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024580/
https://ncbi.nlm.nih.gov/pubmed/27528673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607011113
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