Controlling cancer-induced inflammation with a nucleic acid scavenger prevents lung metastasis in murine models of breast cancer

Tumor cells release nucleic acid-containing proinflammatory complexes, termed nucleic acid-containing damage-associated molecular patterns (NA DAMPs), passively upon death and actively during stress. NA DAMPs activate pattern recognition receptors on cells in the tumor microenvironment leading to pr...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Holl, Eda K., Frazier, Victoria, Landa, Karenia, Boczkowski, David, Sullenger, Bruce, Nair, Smita K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2021
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116567/
https://ncbi.nlm.nih.gov/pubmed/33348055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.12.026
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