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Crystal structures of the bifunctional tRNA methyltransferase Trm5a

tRNA methyltransferase Trm5 catalyses the transfer of a methyl group from S-adenosyl-L-methionine to G37 in eukaryotes and archaea. The N1-methylated guanosine is the product of the initial step of the wyosine hypermodification, which is essential for the maintenance of the reading frame during tran...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Wang, Caiyan, Jia, Qian, Chen, Ran, Wei, Yuming, Li, Juntao, Ma, Jie, Xie, Wei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024318/
https://ncbi.nlm.nih.gov/pubmed/27629654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33553
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