Crystal structure of tRNA m(1)G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate

Transfer RNA (tRNA) methylation is necessary for the proper biological function of tRNA. The N(1) methylation of guanine at Position 9 (m(1)G9) of tRNA, which is widely identified in eukaryotes and archaea, was found to be catalyzed by the Trm10 family of methyltransferases (MTases). Here, we report...

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Detalhes bibliográficos
Main Authors: Shao, Zhenhua, Yan, Wei, Peng, Junhui, Zuo, Xiaobing, Zou, Yang, Li, Fudong, Gong, Deshun, Ma, Rongsheng, Wu, Jihui, Shi, Yunyu, Zhang, Zhiyong, Teng, Maikun, Li, Xu, Gong, Qingguo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874184/
https://ncbi.nlm.nih.gov/pubmed/24081582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt869
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