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The methyltransferase TrmA facilitates tRNA folding through interaction with its RNA-binding domain

tRNAs are the most highly modified RNAs in all cells, and formation of 5-methyluridine (m(5)U) at position 54 in the T arm is a common RNA modification found in all tRNAs. The m(5)U modification is generated by the methyltransferase TrmA. Here, we test and prove the hypothesis that Escherichia coli...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Keffer-Wilkes, Laura Carole, Soon, Emily F, Kothe, Ute
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641329/
https://ncbi.nlm.nih.gov/pubmed/32597953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa548
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