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High cell-surface density of HER2 deforms cell membranes
Breast cancers (BC) with HER2 overexpression (referred to as HER2 positive) progress more aggressively than those with normal expression. Targeted therapies against HER2 can successfully delay the progression of HER2-positive BC, but details of how this overexpression drives the disease are not full...
Enregistré dans:
Publié dans: | Nat Commun |
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Auteurs principaux: | , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Nature Publishing Group
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5023959/ https://ncbi.nlm.nih.gov/pubmed/27599456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12742 |
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