A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene

Mutagenesis screening is a powerful forward genetic approach that has been successfully applied in lower-model organisms to discover genetic factors for biological processes. This phenotype-based approach has yet to be established in vertebrates for probing major human diseases, largely because of t...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Ding, Yonghe, Long, Pamela A., Bos, J. Martijn, Shih, Yu-Huan, Ma, Xiao, Sundsbak, Rhianna S., Chen, Jianhua, Jiang, Yiwen, Zhao, Liqun, Hu, Xinyang, Wang, Jianan, Shi, Yongyong, Ackerman, Michael J., Lin, Xueying, Ekker, Stephen C., Redfield, Margaret M., Olson, Timothy M., Xu, Xiaolei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023154/
https://ncbi.nlm.nih.gov/pubmed/27642634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88797
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