Haploinsufficiency of Target of Rapamycin Attenuates Cardiomyopathies in Adult Zebrafish

RATIONALE: Although a cardioprotective function of target of rapamycin (TOR) signaling inhibition has been suggested by pharmacological studies using rapamycin, genetic evidences are still lacking. Here, we explored adult zebrafish as a novel vertebrate model for dissecting signaling pathways in car...

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Main Authors: Ding, Yonghe, Sun, Xiaojing, Huang, Wei, Hoage, Tiffany, Redfield, Margaret, Kushwaha, Sudhir, Sivasubbu, Sridhar, Lin, Xueying, Ekker, Stephen, Xu, Xiaolei
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166359/
https://ncbi.nlm.nih.gov/pubmed/21757652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.248260
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