Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish

The adult zebrafish is an emerging vertebrate model for studying human cardiomyopathies; however, whether the simple zebrafish heart can model different subtypes of cardiomyopathies, such as dilated cardiomyopathy (DCM), remains elusive. Here, we generated and characterized an inherited DCM model in...

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Bibliographische Detailangaben
Veröffentlicht in:Dis Model Mech
Hauptverfasser: Ding, Yonghe, Dvornikov, Alexey V., Ma, Xiao, Zhang, Hong, Wang, Yong, Lowerison, Matthew, Packard, Rene R., Wang, Lei, Chen, Jun, Zhang, Yuji, Hsiai, Tzung, Lin, Xueying, Xu, Xiaolei
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826022/
https://ncbi.nlm.nih.gov/pubmed/31492659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.040154
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