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Synthesis of α-l-Threofuranosyl Nucleoside Triphosphates (tNTPs)

[Image: see text] The α-l-threofuranosyl nucleoside triphosphates of T, G, and D (tTTP, tGTP, and tDTP) were synthesized from the described 2‘-O-DMT-protected derivatives using the Eckstein method, while the corresponding C derivative (tCTP) was prepared from the 2‘-O-acetyl derivative. The prepared...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Zou, Keyong, Horhota, Allen, Yu, Biao, Szostak, Jack W., McLaughlin, Larry W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2005
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022784/
https://ncbi.nlm.nih.gov/pubmed/15816733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol050081+
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