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Synthesis and Properties of α-Phosphate-Modified Nucleoside Triphosphates

This review article is focused on the progress made in the synthesis of 5′-α-P-modified nucleoside triphosphates (α-phosphate mimetics). A variety of α-P-modified nucleoside triphosphates (NTPαXYs, Y = O, S; X = S, Se, BH<sub>3</sub>, alkyl, amine, N-alkyl, imido, or others) have been developed. The...

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Main Authors: Alina I. Novgorodtseva, Alexander A. Lomzov, Svetlana V. Vasilyeva
Format: Artigo
Language:Inglês
Published: MDPI AG 2024-08-01
Series:Molecules
Subjects:
α-phosphate mimetic
α-P-modified nucleoside triphosphate
cyclotriphosphite intermediate
5′-(α-P-thio)nucleoside triphosphate
5′-(α-P-seleno)nucleoside triphosphate
5′-(α-P-borano)nucleoside triphosphate
Online Access:https://www.mdpi.com/1420-3049/29/17/4121
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