Responsiveness to IL-7 but not to IFN-α is diminished in CD4 T cells from treated HIV infected patients who experience poor CD4 T cell recovery

OBJECTIVE: To assess CD4+ T cell responsiveness to IL-7 and IFN-α in HIV infected patients who experience poor recovery of CD4 T cell counts during therapy (immune failure subjects). DESIGN: Responses to IL-7 and IFN-α were compared between HIV infected immune failure (CD4 counts < 379) subjects...

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Bibliographic Details
Published in:AIDS
Main Authors: Nguyen, Thao P., Shukla, Supriya, Asaad, Robert, Freeman, Michael L., Lederman, Michael M., Harding, Clifford V., Sieg, Scott F.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022566/
https://ncbi.nlm.nih.gov/pubmed/27191978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001161
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