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Cytomegalovirus-specific responses of CD38(+) memory T cells are skewed towards IFN-γ and dissociated from CD154 in HIV-1 infection

OBJECTIVE: Despite the strong correlation of T-cell CD38 expression with HIV disease progression, evidence linking CD38 expression and dysfunction at the single cell level is scant. Since CD38(+) memory CD4(+) T cells, especially those from HIV-infected persons, fail to induce CD154 (CD40L) while re...

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Detalhes bibliográficos
Main Authors: Olvera-García, Gustavo, Espinosa, Enrique, Sieg, Scott F., Lederman, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109327/
https://ncbi.nlm.nih.gov/pubmed/24594993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000162
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