Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy

BACKGROUND: Peripheral inflammation contributes to the neurological alterations in hepatic encephalopathy (HE). Neuroinflammation and altered GABAergic neurotransmission mediate cognitive and motor alterations in rats with HE. It remains unclear (a) if neuroinflammation and neurological impairment i...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Dadsetan, Sherry, Balzano, Tiziano, Forteza, Jerónimo, Agusti, Ana, Cabrera-Pastor, Andrea, Taoro-Gonzalez, Lucas, Hernandez-Rabaza, Vicente, Gomez-Gimenez, Belen, ElMlili, Nisrin, Llansola, Marta, Felipo, Vicente
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022234/
https://ncbi.nlm.nih.gov/pubmed/27623772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0710-8
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