Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy

Stroke is a highly debilitating, often fatal disorder for which current therapies are suitable for only a minor fraction of patients. Discovery of novel, effective therapies is hampered by the fact that advanced age, primary age-related tauopathy or comorbidities typical to several types of dementin...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Huuskonen, Mikko T., Loppi, Sanna, Dhungana, Hiramani, Keksa-Goldsteine, Velta, Lemarchant, Sighild, Korhonen, Paula, Wojciechowski, Sara, Pollari, Eveliina, Valonen, Piia, Koponen, Juho, Takashima, Akihiko, Landreth, Gary, Goldsteins, Gundars, Malm, Tarja, Koistinaho, Jari, Kanninen, Katja M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021977/
https://ncbi.nlm.nih.gov/pubmed/27624652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33176
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki