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Tandemly Integrated HPV16 Can Form a Brd4-Dependent Super-Enhancer-Like Element That Drives Transcription of Viral Oncogenes

In cancer cells associated with human papillomavirus (HPV) infections, the viral genome is very often found integrated into the cellular genome. The viral oncogenes E6 and E7 are transcribed from the viral promoter, and integration events that alter transcriptional regulation of this promoter contri...

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Pubblicato in:mBio
Autori principali: Dooley, Katharine E., Warburton, Alix, McBride, Alison A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021809/
https://ncbi.nlm.nih.gov/pubmed/27624132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01446-16
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