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Persistence of an Oncogenic Papillomavirus Genome Requires cis Elements from the Viral Transcriptional Enhancer

Human papillomavirus (HPV) genomes are replicated and maintained as extrachromosomal plasmids during persistent infection. The viral E2 proteins are thought to promote stable maintenance replication by tethering the viral DNA to host chromatin. However, this has been very difficult to prove genetica...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Van Doorslaer, Koenraad, Chen, Dan, Chapman, Sandra, Khan, Jameela, McBride, Alison A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698554/
https://ncbi.nlm.nih.gov/pubmed/29162712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01758-17
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