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Persistence of an Oncogenic Papillomavirus Genome Requires cis Elements from the Viral Transcriptional Enhancer

Human papillomavirus (HPV) genomes are replicated and maintained as extrachromosomal plasmids during persistent infection. The viral E2 proteins are thought to promote stable maintenance replication by tethering the viral DNA to host chromatin. However, this has been very difficult to prove genetica...

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Foilsithe in:mBio
Main Authors: Van Doorslaer, Koenraad, Chen, Dan, Chapman, Sandra, Khan, Jameela, McBride, Alison A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698554/
https://ncbi.nlm.nih.gov/pubmed/29162712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01758-17
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