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Persistence of an Oncogenic Papillomavirus Genome Requires cis Elements from the Viral Transcriptional Enhancer

Human papillomavirus (HPV) genomes are replicated and maintained as extrachromosomal plasmids during persistent infection. The viral E2 proteins are thought to promote stable maintenance replication by tethering the viral DNA to host chromatin. However, this has been very difficult to prove genetica...

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Podrobná bibliografie
Vydáno v:mBio
Hlavní autoři: Van Doorslaer, Koenraad, Chen, Dan, Chapman, Sandra, Khan, Jameela, McBride, Alison A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698554/
https://ncbi.nlm.nih.gov/pubmed/29162712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01758-17
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