mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3

OBJECTIVE: We have recently shown that acute inhibition of both mTOR complexes (mTORC1 and mTORC2) increases whole-body lipid utilization, while mTORC1 inhibition had no effect. Therefore, we tested the hypothesis that mTORC2 regulates lipid metabolism in skeletal muscle. METHODS: Body composition,...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Kleinert, Maximilian, Parker, Benjamin L., Chaudhuri, Rima, Fazakerley, Daniel J., Serup, Annette, Thomas, Kristen C., Krycer, James R., Sylow, Lykke, Fritzen, Andreas M., Hoffman, Nolan J., Jeppesen, Jacob, Schjerling, Peter, Ruegg, Markus A., Kiens, Bente, James, David E., Richter, Erik A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021677/
https://ncbi.nlm.nih.gov/pubmed/27656402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.06.007
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