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Generation and Characterization of Tamoxifen-Inducible Pax9-CreER Knock-In Mice using CrispR/Cas9
Pax9 encodes a paired-box homeodomain transcription factor and is critical for the development of multiple organs. Using CrispR/Cas9-mediated homologous directed repair (HDR), we generated a new Pax9-CreER knock-in mouse line in which the CreER(T2) fusion protein is produced after synthesis of endog...
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Publicado no: | Genesis |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5021577/ https://ncbi.nlm.nih.gov/pubmed/27381449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22956 |
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