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Generation and Characterization of Tamoxifen-Inducible Pax9-CreER Knock-In Mice using CrispR/Cas9

Pax9 encodes a paired-box homeodomain transcription factor and is critical for the development of multiple organs. Using CrispR/Cas9-mediated homologous directed repair (HDR), we generated a new Pax9-CreER knock-in mouse line in which the CreER(T2) fusion protein is produced after synthesis of endog...

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Detalhes bibliográficos
Publicado no:Genesis
Main Authors: Feng, Jifan, Jing, Junjun, Sanchez-Lara, Pedro A, Bootwalla, Moiz S, Buckley, Jonathan, Wu, Nancy, Yan, Youzhen, Chai, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021577/
https://ncbi.nlm.nih.gov/pubmed/27381449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22956
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