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A Single Mutation in the VP1 of Enterovirus 71 Is Responsible for Increased Virulence and Neurotropism in Adult Interferon-Deficient Mice

Hand, foot, and mouth disease (HFMD) has spread throughout the Asia-Pacific region, affecting millions of young children, who develop symptoms ranging from painful blisters around their mouths and hands to neurological complications. Many members of the genus Enterovirus (family Picornaviridae) caus...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Caine, Elizabeth A., Moncla, Louise H., Ronderos, Monica D., Friedrich, Thomas C., Osorio, Jorge E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021399/
https://ncbi.nlm.nih.gov/pubmed/27440896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01370-16
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