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A Single Mutation in the VP1 of Enterovirus 71 Is Responsible for Increased Virulence and Neurotropism in Adult Interferon-Deficient Mice

Hand, foot, and mouth disease (HFMD) has spread throughout the Asia-Pacific region, affecting millions of young children, who develop symptoms ranging from painful blisters around their mouths and hands to neurological complications. Many members of the genus Enterovirus (family Picornaviridae) caus...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Caine, Elizabeth A., Moncla, Louise H., Ronderos, Monica D., Friedrich, Thomas C., Osorio, Jorge E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021399/
https://ncbi.nlm.nih.gov/pubmed/27440896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01370-16
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