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The Interferon-Stimulated Gene IFITM3 Restricts Infection and Pathogenesis of Arthritogenic and Encephalitic Alphaviruses

Host cells respond to viral infections by producing type I interferon (IFN), which induces the expression of hundreds of interferon-stimulated genes (ISGs). Although ISGs mediate a protective state against many pathogens, the antiviral functions of the majority of these genes have not been identifie...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Poddar, Subhajit, Hyde, Jennifer L., Gorman, Matthew J., Farzan, Michael, Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021394/
https://ncbi.nlm.nih.gov/pubmed/27440901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00655-16
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