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5′-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion

Invadopodia are specialized membrane protrusions that support degradation of extracellular matrix (ECM) by cancer cells, allowing invasion and metastatic spread. Although early stages of invadopodia assembly have been elucidated, little is known about maturation of invadopodia into structures compet...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Rajadurai, Charles V., Havrylov, Serhiy, Coelho, Paula P., Ratcliffe, Colin D.H., Zaoui, Kossay, Huang, Bruce H., Monast, Anie, Chughtai, Naila, Sangwan, Veena, Gertler, Frank B., Siegel, Peter M., Park, Morag
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021089/
https://ncbi.nlm.nih.gov/pubmed/27597754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201501003
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