5′-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion

Invadopodia are specialized membrane protrusions that support degradation of extracellular matrix (ECM) by cancer cells, allowing invasion and metastatic spread. Although early stages of invadopodia assembly have been elucidated, little is known about maturation of invadopodia into structures compet...

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Vydáno v:J Cell Biol
Hlavní autoři: Rajadurai, Charles V., Havrylov, Serhiy, Coelho, Paula P., Ratcliffe, Colin D.H., Zaoui, Kossay, Huang, Bruce H., Monast, Anie, Chughtai, Naila, Sangwan, Veena, Gertler, Frank B., Siegel, Peter M., Park, Morag
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021089/
https://ncbi.nlm.nih.gov/pubmed/27597754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201501003
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