5′-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion

Invadopodia are specialized membrane protrusions that support degradation of extracellular matrix (ECM) by cancer cells, allowing invasion and metastatic spread. Although early stages of invadopodia assembly have been elucidated, little is known about maturation of invadopodia into structures compet...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Rajadurai, Charles V., Havrylov, Serhiy, Coelho, Paula P., Ratcliffe, Colin D.H., Zaoui, Kossay, Huang, Bruce H., Monast, Anie, Chughtai, Naila, Sangwan, Veena, Gertler, Frank B., Siegel, Peter M., Park, Morag
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2016
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021089/
https://ncbi.nlm.nih.gov/pubmed/27597754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201501003
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