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Behavioral and biochemical effects of ketamine and dextromethorphan relative to its antidepressant-like effects in Swiss Webster mice

Ketamine has been shown to produce rapid and robust antidepressant effects in depressed individuals, however its abuse potential and adverse psychotomimetic effects limit its widespread use. Dextromethorphan may serve as a safer alternative based on pharmacodynamic similarities to ketamine. In this...

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Bibliografiske detaljer
Udgivet i:Neuroreport
Main Authors: Nguyen, Linda, Lucke-Wold, Brandon P., Logsdon, Aric F., Scandinaro, Anna L., Huber, Jason D., Matsumoto, Rae R.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020901/
https://ncbi.nlm.nih.gov/pubmed/27580401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000646
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