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Behavioral and biochemical effects of ketamine and dextromethorphan relative to its antidepressant-like effects in Swiss Webster mice

Ketamine has been shown to produce rapid and robust antidepressant effects in depressed individuals, however its abuse potential and adverse psychotomimetic effects limit its widespread use. Dextromethorphan may serve as a safer alternative based on pharmacodynamic similarities to ketamine. In this...

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Vydáno v:Neuroreport
Hlavní autoři: Nguyen, Linda, Lucke-Wold, Brandon P., Logsdon, Aric F., Scandinaro, Anna L., Huber, Jason D., Matsumoto, Rae R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020901/
https://ncbi.nlm.nih.gov/pubmed/27580401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000646
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