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Behavioral and biochemical effects of ketamine and dextromethorphan relative to its antidepressant-like effects in Swiss Webster mice

Ketamine has been shown to produce rapid and robust antidepressant effects in depressed individuals, however its abuse potential and adverse psychotomimetic effects limit its widespread use. Dextromethorphan may serve as a safer alternative based on pharmacodynamic similarities to ketamine. In this...

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Detalhes bibliográficos
Publicado no:Neuroreport
Main Authors: Nguyen, Linda, Lucke-Wold, Brandon P., Logsdon, Aric F., Scandinaro, Anna L., Huber, Jason D., Matsumoto, Rae R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020901/
https://ncbi.nlm.nih.gov/pubmed/27580401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000646
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