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Behavioral and biochemical effects of ketamine and dextromethorphan relative to its antidepressant-like effects in Swiss Webster mice

Ketamine has been shown to produce rapid and robust antidepressant effects in depressed individuals, however its abuse potential and adverse psychotomimetic effects limit its widespread use. Dextromethorphan may serve as a safer alternative based on pharmacodynamic similarities to ketamine. In this...

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Bibliografske podrobnosti
izdano v:Neuroreport
Main Authors: Nguyen, Linda, Lucke-Wold, Brandon P., Logsdon, Aric F., Scandinaro, Anna L., Huber, Jason D., Matsumoto, Rae R.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020901/
https://ncbi.nlm.nih.gov/pubmed/27580401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000646
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