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Behavioral and biochemical effects of ketamine and dextromethorphan relative to its antidepressant-like effects in Swiss Webster mice

Ketamine has been shown to produce rapid and robust antidepressant effects in depressed individuals, however its abuse potential and adverse psychotomimetic effects limit its widespread use. Dextromethorphan may serve as a safer alternative based on pharmacodynamic similarities to ketamine. In this...

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Publicat a:Neuroreport
Autors principals: Nguyen, Linda, Lucke-Wold, Brandon P., Logsdon, Aric F., Scandinaro, Anna L., Huber, Jason D., Matsumoto, Rae R.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020901/
https://ncbi.nlm.nih.gov/pubmed/27580401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000646
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