Autoantibodies against a serine tRNA-protein complex implicated in cotranslational selenocysteine insertion.

We describe an autoantibody specificity present in a subgroup of patients with a severe form of autoimmune chronic active hepatitis. These antibodies precipitate a 90-nucleotide RNA from human whole cell extracts and recognize a 48-kDa polypeptide in immunoblotting assays. The RNA is a UGA suppresso...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gelpi, C, Sontheimer, E J, Rodriguez-Sanchez, J L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50208/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409691/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.20.9739
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