Autoantibodies against a serine tRNA-protein complex implicated in cotranslational selenocysteine insertion.
We describe an autoantibody specificity present in a subgroup of patients with a severe form of autoimmune chronic active hepatitis. These antibodies precipitate a 90-nucleotide RNA from human whole cell extracts and recognize a 48-kDa polypeptide in immunoblotting assays. The RNA is a UGA suppresso...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1992
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50208/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409691/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.20.9739 |
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