Autoantibodies against a serine tRNA-protein complex implicated in cotranslational selenocysteine insertion.

We describe an autoantibody specificity present in a subgroup of patients with a severe form of autoimmune chronic active hepatitis. These antibodies precipitate a 90-nucleotide RNA from human whole cell extracts and recognize a 48-kDa polypeptide in immunoblotting assays. The RNA is a UGA suppresso...

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Hauptverfasser: Gelpi, C, Sontheimer, E J, Rodriguez-Sanchez, J L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC50208/
https://ncbi.nlm.nih.gov/pubmed/1409691
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