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A haplotype-based normalization technique for the analysis and detection of allele specific expression

BACKGROUND: Allele specific expression (ASE) has become an important phenotype, being utilized for the detection of cis-regulatory variation, nonsense mediated decay and imprinting in the personal genome, and has been used to both identify disease loci and consider the penetrance of damaging alleles...

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Опубликовано в: :BMC Bioinformatics
Главные авторы: Hodgkinson, Alan, Grenier, Jean-Christophe, Gbeha, Elias, Awadalla, Philip
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020486/
https://ncbi.nlm.nih.gov/pubmed/27618913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1238-8
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