Selective constraint, background selection, and mutation accumulation variability within and between human populations

BACKGROUND: Regions of the genome that are under evolutionary constraint across multiple species have previously been used to identify functional sequences in the human genome. Furthermore, it is known that there is an inverse relationship between evolutionary constraint and the allele frequency of...

Full description

Saved in:
Bibliographic Details
Main Authors: Hodgkinson, Alan, Casals, Ferran, Idaghdour, Youssef, Grenier, Jean-Christophe, Hernandez, Ryan D, Awadalla, Philip
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727949/
https://ncbi.nlm.nih.gov/pubmed/23875710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-495
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items