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Selective constraint, background selection, and mutation accumulation variability within and between human populations
BACKGROUND: Regions of the genome that are under evolutionary constraint across multiple species have previously been used to identify functional sequences in the human genome. Furthermore, it is known that there is an inverse relationship between evolutionary constraint and the allele frequency of...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3727949/ https://ncbi.nlm.nih.gov/pubmed/23875710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-495 |
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