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Selective constraint, background selection, and mutation accumulation variability within and between human populations

BACKGROUND: Regions of the genome that are under evolutionary constraint across multiple species have previously been used to identify functional sequences in the human genome. Furthermore, it is known that there is an inverse relationship between evolutionary constraint and the allele frequency of...

詳細記述

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書誌詳細
主要な著者: Hodgkinson, Alan, Casals, Ferran, Idaghdour, Youssef, Grenier, Jean-Christophe, Hernandez, Ryan D, Awadalla, Philip
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727949/
https://ncbi.nlm.nih.gov/pubmed/23875710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-495
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